Premature ejaculation is the term used to describe a condition where a man ejaculates too quickly. He might ejaculate in his sleep, or even before penetration has occurred. Some people describe premature ejaculation as “coming too soon.

Premature ejaculation (PE) is a fairly common sexual complaint in men. The estimates vary, but as many as one third of men say they experience it at some point in their lives. If it happens infrequently, it’s not a big deal, but it can be a big deal if it becomes a regular part of your sex life.

If you’re experiencing premature ejaculation, there are a number of things you can do to help, including taking medications, counseling, and practicing better sexual techniques. It can be embarrassing to discuss, but getting treatment can help you find relief.

Dapoxetine is a fairly new drug that’s being marketed as treatment for premature ejaculation. On the whole, the evidence is fairly strong that it does work. But what about the risks? How do you use it? We’ll get into that in this article, so if PM is an issue you’re dealing with, you might want to read on.

What is Dapoxetine?

What is Dapoxetine

Dapoxetine, marketed under the brand name Priligy, is a medication used to treat premature ejaculation (a sexual dysfunction in which a man ejaculates too quickly during sexual intercourse). This medication aids in increasing ejaculation time and achieving better control over ejaculation during sexual intercourse.

The medication is a selective serotonin reuptake inhibitor (SSRI) and it works by slowing down the absorption of serotonin, which then increases the time it takes to send the signal through the nerve that controls the muscles responsible for ejaculation.

How Well Does Dapoxetine Work?

In general, it has been discovered that SSRIs are effective in the treatment of people suffering from premature ejaculation. 

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Priligy was initially developed as a new antidepressant, but it was discovered early in the development process that the medication could also be used to effectively delay orgasm in men. 

Delayed ejaculation is frequently listed as a side effect of any other selective serotonin reuptake inhibitor (SSRI), but this antidepressant is specifically prescribed for that purpose. 

The action of Dapoxetine is considered to be faster than that of other types of SSRIs. Following ingestion, it is rapidly absorbed into the system and eliminated from the body shortly after. 

Dapoxetine has been studied extensively for its effectiveness in delaying the onset of ejaculation on a number of occasions. 

Over the course of all studies, the majority of study participants had their time to ejaculate increased by between half-a-minute to three-and-a-half minutes.

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Dapoxetine’s Mechanism of Action

Dapoxetine’s mechanism of action

Dapoxetine, a drug approved for the treatment of premature ejaculation (PE) in men aged 18–64 years, is a selective serotonin reuptake inhibitor (SSRI). It belongs to the group of fast-acting antidepressants called serotonin specific reuptake inhibitors (SSRIs).

This drug is typically used once a day, 1-3 hours before sexual encounters, as a “on-demand” medication. After ingestion, it is absorbed from the gastrointestinal tract in a short period of time, reaching its maximum plasma concentration approximately 1 hour after ingestion. It is then rapidly eliminated, meaning that it does not build up in the body. 

It is true that the pharmacokinetics of the drug are affected by the dose, but it is not affected by the consumption of food or alcohol. Priligy is metabolized in the liver to a variety of substances, including desmethyl dipoxetine and didemethyl dipoxetine, among others.

The metabolites are broken down by the liver and eliminated through the kidneys. Because of this, it should not be used in patients with liver and kidney damage or those taking drugs that affect cytochrome.

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Dapoxetine Side Effects

One of the most concerning aspects of Dapoxetine is that it may increase blood pressure in some patients. While the manufacturer claims that the drug’s side effects are only minor and temporary, it does list several more serious side effects that may be experienced by some people. These include:

  • Feeling faint or dizzy when you stand up
  • Tingling, numbness, or trembling
  • Eye pain or blurred vision
  • Ringing in the ears or changes in hearing
  • Increase in blood pressure
  • Feelings of anxiety, nervousness, indifference, or depression

In rare cases, men can have a negative reaction to Dapoxetine and experience decreased sexual desire and erectile dysfunction. 

Before using a medication, carefully read the package insert, which contains information on the indications, contraindications, side effects, and dosage, as well as instructions on how to use the medication, or consult your doctor or pharmacist, as each medication used improperly poses a threat to your life or health.

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Dapoxetine Dosage

Dapoxetine Dosage

Priligy can be taken with or without food depending on your preference. When using this preparation for the first time, it is recommended that you take 30 mg / day one to three hours before the planned sexual encounter. In some cases, the drug’s dose may be increased to 60 mg per day, depending on its effect. Priligy is not a medication that can be taken on a daily basis for an extended period of time. It is recommended that the benefits of using this preparation be weighed against the risks associated with its frequent use after at least six doses have been taken.


Priligy is a safe and effective oral medication for erectile dysfunction that is well tolerated and easy to administer. It increases the duration of sex significantly.

Dapoxetine is an approved treatment for PE, and there are other alternatives to consider for other patients. If your doctor suggests dapoxetine or other treatments, look into these options before making a decision.

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Therapies for sexual dysfunction are increasingly common in doctors’ offices. Sometimes doctors even prescribe treatments that have nothing to do with sexual dysfunction. However, you can still ask your doctor about these medications and discuss treatment options with your spouse.

In conclusion, it can be said that the treatment of premature ejaculation is possible with dapoxetine and should be undertaken by doctors of different specialties who treat patients with this problem.

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Frequently Asked Questions

1. How long does dapoxetine make you last?

Dapoxetine is most effective within 1-3 hours of taking it, but it can sometimes be effective for up to 12 hours after taking it. 

According to the study, about 8 out of 10 men find Priligy to be effective. They should notice a two- to threefold increase in the amount of time their erection lasts before they have to ejaculate. 

2. Can I Take Dapoxetine Daily?

It can be taken with or without food, depending on your doctor’s instructions. It is typically taken as needed, one to three hours before sexual activity, depending on the individual. This drug is not intended for daily use, and it is best not to take more than one tablet a day.

3. Where Can I Get Dapoxetine?

If you are 18 years of age or older, you may purchase Dapoxetine without a prescription. Check with your doctor or pharmacist if you have any concerns or need assistance with ordering Dapoxetine. 

4. How long does it take Dapoxetine to work?

It usually takes Dapoxetine three to four hours to start working. After that time it will take about another half-hour for the effects to become fully felt. You may notice an effect within 30 minutes. If you are taking the drug for the first time, be sure to follow all instructions on the package to ensure the best results.

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